Antibiotic Therapy for Klebsiella pneumoniae Bacteremia: Implications of Production of Extended-Spectrum -Lactamases

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Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases.

The prevalence of extended-spectrum beta -lactamase (ESBL) production by Klebsiella pneumonia approaches 50% in some countries, with particularly high rates in eastern Europe and Latin America. No randomized trials have ever been performed on treatment of bacteremia due to ESBL-producing organisms; existing data comes only from retrospective, single-institution studies. In a prospective study o...

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1 The Laboratory for Molecular Epidemiology and Antibiotic Research, Division of Epidemiology, Tel Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. 2 Clinical Microbiology Laboratory, Ha'Emek Medical Center, Afula, Israel 3 Department of Cinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Av...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2004

ISSN: 1058-4838,1537-6591

DOI: 10.1086/420816